Author

P. H. Lizotte

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Akitsu· 1 shared A. Stafford· 1 shared C. M. Messier· 1 shared D. A. Barbie· 1 shared D. J. Mooney· 1 shared E. A. Chiocca· 1 shared E. H. Knelson· 1 shared E. L. Reinherz· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. Akitsu

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Pre-T cell receptor Self-MHC Sampling Restricts Thymocyte Dedifferentiation

J. S. Duke-Cohan, A. Akitsu, R. J. Mallis, C. M. Messier, P. H. Lizotte, W. Hwang, M. J. Lang, E. L. Reinherz

The paper shows that preTCR-pMHC interactions prevent thymocyte dedifferentiation by analyzing single-cell transcriptomes in fetal thymic cultures with and without pMHC.

bioRxiv · Apr 28, 2022Immunology

STING activation promotes robust immune response and NK cell-mediated tumor regression in glioblastoma models

G. Berger, E. H. Knelson, J. L. Jimenez-Macias, M. O. Nowicki, S. Han, P. H. Lizotte, K. Adu-Berchie, A. Stafford, N. Dimitrikakis, E. A. Chiocca, D. J. Mooney, D. A. Barbie, S. E. Lawler

This study shows that STING activation in glioblastoma models enhances immune responses and NK cell-mediated tumor regression, with long-term survival benefits in murine models.

bioRxiv · Feb 28, 2022 · PreprintCancer Biology