Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis
A. Acosta-Serrano, M. Sterkel, L. Haines, A. Casas-Sanchez, V. Owino, R. Vionette-Amaral, S. Quek, C. Rose, M. Silva dos Santos, N. Garcia Escude, H. Ismail, M. I. Paine, S. M. Barribeau, S. Wagstaff, J. I. MacRae, , P. L. Oliveira
This study shows that nitisinone can kill tsetse flies without harming bees, offering an eco-friendly method to control African trypanosomiasis transmission.
bioRxiv · Jun 8, 2020Biochemistry