A. Nyska

Iron Regulatory Protein 1 is Required for the Propagation of Inflammation in Inflammatory Bowel Disease

This study identifies IRP1 as a key driver of inflammation in IBD by linking iron homeostasis disruption to inflammatory propagation.

Autophagy controls mucus secretion from intestinal goblet cells by alleviating ER stress

This study shows that autophagy regulates mucus secretion in intestinal goblet cells by reducing ER stress, thereby maintaining intestinal homeostasis.

Melanocyte-secreted Fibromodulin constrains skin inflammation in mice injected with lupus serum

This study shows that low melanocyte-secreted fibromodulin (FMOD) and reduced pigmentation in mice correlate with increased skin inflammation when exposed to lupus serum.

Nonclinical Safety and Immunogenicity of an rVSV-ΔG-SARS-CoV-2-S vaccine in mice, hamsters, rabbits and pigs

This study evaluates the safety, immunogenicity, and efficacy of an rVSV-ΔG-SARS-CoV-2-S vaccine in multiple animal species, finding no adverse effects and a robust immune response.

COVID-eVax, an electroporated plasmid DNA vaccine candidate encoding the SARS-CoV-2 Receptor Binding Domain, elicits protective immune responses in animal models of COVID-19

This paper evaluates a DNA vaccine candidate, COVID-eVax, which induces strong neutralizing antibodies and T cell responses against SARS-CoV-2 in animal models, showing protective effects against viral challenge.