Author

N. Hruschka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Organism:mouse· 1

Frequent Co-Authors

F. X. Real· 2 shared P. Martinelli· 2 shared A. De Reynies· 1 shared A. Lluch· 1 shared A. Prat· 1 shared A. Sagrera· 1 shared B. Bermejo· 1 shared B. Kloesch· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

F. X. Real

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2 papers

Recent·Most cited

A GATA6-centered gene regulatory network involving HNFs and ΔNp63 controls plasticity and immune escape in pancreatic cancer

P. Martinelli, B. Kloesch, N. Hruschka, V. Ionasz, R. Oellinger, S. Mueller, J. Martinez de Villareal, H. P. Dienes, M. Schindl, E. Gruber, J. Stift, G. A. Lomberk, B. Seidler, D. Saur, R. Rad, , F. X. Real

This paper identifies a GATA6-centered gene regulatory network involving HNFs and ΔNp63 that controls plasticity and immune escape in pancreatic cancer, showing GATA6 loss is necessary but not sufficient for the basal phenotype.

Gut · Apr 12, 2021Peer-reviewedCancer Biology

The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver

N. Hruschka, M. Subijana, O. Grana-Castro, F. Del Cano-Ochoa, L. Pare Brunet, A. Sagrera, A. De Reynies, D. Andreu, J. Sutton, I. Chernukhin, S.-F. Chin, C. Caldas, A. Lluch, O. Burgues, B. Bermejo, , P. Martinelli

The paper investigates the context-dependent oncogenic effects of the GATA3 X308_Splice mutation in breast cancer, showing its differential impact based on hormonal status.

bioRxiv · Jun 8, 2019Cancer Biology