Author

N. I. Callaghan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

C. A. Simmons· 3 shared A. O. Gramolini· 2 shared M. Radisic· 2 shared A. Driouchi· 1 shared A. I. Shukalyuk· 1 shared C. M. Yip· 1 shared D. M. Kilkenny· 1 shared E. M. Strohm· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersBioengineering

C. A. Simmons

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Advanced physiological maturation of iPSC-derived human cardiomyocytes using an algorithm-directed optimization of defined media components

N. I. Callaghan, L. J. Durland, W. Chen, U. Kuzmanov, M. Z. Miranda, Z. Mirzaei, R. G. Ireland, E. Y. Wang, K. Wagner, M. M. Kim, J. Audet, P. Santerre, A. O. Gramolini, F. Billia, M. Radisic, , C. A. Simmons

This study develops a novel medium for iPSC-derived cardiomyocytes using differential evolution to enhance maturation, validated through multiomic analysis.

bioRxiv · Oct 10, 2022Bioengineering

Non-invasive quantification of contractile dynamics in cardiac cells, spheroids and organs-on-a-chip using high frequency ultrasound

E. M. Strohm, N. I. Callaghan, N. Latifi, N. Rafatian, S. Funakoshi, I. Fernandes, M. Radisic, G. Keller, M. Kolios, C. A. Simmons

This paper develops a high-frequency ultrasound technique to non-invasively measure contractile dynamics in cardiac cells, spheroids, and organs-on-a-chip, showing its ability to quantify beat rate, rhythm, and force with high temporal resolution.

bioRxiv · Jun 28, 2022 · PreprintBioengineering

Long-term functional culture and in vitro manipulation of adult mouse cardiomyocytes

N. I. Callaghan, S.-H. Lee, S. Hadipour-Lakmehsari, X. A. Lee, M. A. Siraj, A. Driouchi, C. M. Yip, M. Husain, C. A. Simmons, A. O. Gramolini

This study develops methods to culture adult mouse cardiomyocytes long-term, maintaining their structure and function for in vitro experiments and genetic manipulations.

Communications Biology · May 11, 2020Peer-reviewedCell Biology

Enhancing senior high school student engagement and academic performance using an inclusive and scalable inquiry-based program

L. Davenport Huyer, N. I. Callaghan, S. Dicks, E. Scherer, A. I. Shukalyuk, M. Jou, D. M. Kilkenny

This paper describes an inquiry-based program that improves high school student engagement and academic performance in STEM, particularly for under-performing and repeat cohorts.

bioRxiv · Dec 2, 2019 · PreprintScientific Communication & Education