Author

M. Radisic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 7

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 5 Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:imaging· 2

Frequent Co-Authors

N. Rafatian· 3 shared C. A. Simmons· 2 shared G. Keller· 2 shared I. Fernandes· 2 shared K. T. Wagner· 2 shared N. I. Callaghan· 2 shared Y. Zhao· 2 shared A. Andreazza· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersBioengineering

N. Rafatian

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7 papers

Recent·Most cited

Quantitative Image Analysis of Tissue Properties: A MATLAB Tool for Measuring Morphology and Co-localization in 2D Images

S. Landau, E. Shor, M. Radisic, S. Levenberg

The paper introduces a MATLAB tool for quantitatively analyzing 2D tissue images, measuring morphology and co-localization parameters with flexibility across different tissue types.

bioRxiv · Apr 3, 2024 · PreprintBioengineering

Biomimetic fractal topography enhances podocyte maturation in vitro

C. Liu, P. Aggarwal, K. T. Wagner, S. S. Landau, T. Cui, X. Song, L. Shamaei, N. Rafatian, Y. Zhao, S. Rodriguez-Ramirez, K. Morton, E. Virlee, C. Y. Li, D. Bannerman, S. Pascual-Gil, , M. Radisic

This study shows that biomimetic fractal topography improves podocyte maturation in vitro by enhancing marker expression, cell polarity, and ECM remodeling via YAP signaling.

bioRxiv · Mar 16, 2024Bioengineering

Heart-on-a-chip model of immune-induced cardiac dysfunction reveals the involvement of free mitochondrial DNA and therapeutic effects of endothelial exosomes

X. Z. Lu, N. Rafatian, Y. Zhao, K. T. Wagner, E. L. Beroncal, B. Li, C. Lee, J. Chen, E. Churcher, D. Vosoughi, Y. Wang, A. Baker, U. Trahtemberg, B. Li, A. Pierro, , M. Radisic

This paper develops a heart-on-a-chip model to study immune-induced cardiac dysfunction, identifying mitochondrial DNA as a key factor and showing therapeutic potential of endothelial exosomes.

bioRxiv · Aug 9, 2023 · PreprintBioengineering

High-Resolution Additive Manufacturing of a Biodegradable Elastomer with a Low-Cost LCD 3D Printer

V. Karamzadeh, M. Shen, H. Ravanbakhsh, A. S. Kashani, H. Savoji, M. Radisic, D. Juncker

This paper develops a VP-POMaC ink for high-resolution 3D printing using low-cost LCD printers, enabling biodegradable and elastomeric structures with tunable mechanical properties.

bioRxiv · Jun 15, 2023Bioengineering

Advanced physiological maturation of iPSC-derived human cardiomyocytes using an algorithm-directed optimization of defined media components

N. I. Callaghan, L. J. Durland, W. Chen, U. Kuzmanov, M. Z. Miranda, Z. Mirzaei, R. G. Ireland, E. Y. Wang, K. Wagner, M. M. Kim, J. Audet, P. Santerre, A. O. Gramolini, F. Billia, M. Radisic, , C. A. Simmons

This study develops a novel medium for iPSC-derived cardiomyocytes using differential evolution to enhance maturation, validated through multiomic analysis.

bioRxiv · Oct 10, 2022Bioengineering

Non-invasive quantification of contractile dynamics in cardiac cells, spheroids and organs-on-a-chip using high frequency ultrasound

E. M. Strohm, N. I. Callaghan, N. Latifi, N. Rafatian, S. Funakoshi, I. Fernandes, M. Radisic, G. Keller, M. Kolios, C. A. Simmons

This paper develops a high-frequency ultrasound technique to non-invasively measure contractile dynamics in cardiac cells, spheroids, and organs-on-a-chip, showing its ability to quantify beat rate, rhythm, and force with high temporal resolution.

bioRxiv · Jun 28, 2022 · PreprintBioengineering

Functional arrays of human pluripotent stem cell-derived cardiac microtissues

N. Thavandiran, C. Hale, P. Blit, M. L. Sandberg, M. E. McElvain, M. Gagliardi, B. Sun, A. Witty, G. Graham, M. McIntosh, M. A. Bakooshli, H. Le, J. Ostblom, S. McEwen, E. Chau, , P. Zandstra

This paper develops a 96-well platform of cardiac microtissues to measure contractile force for drug screening and tissue engineering.

bioRxiv · Mar 5, 2019Bioengineering