Author

N. J. Mokiem

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1 Organism:virus· 1

Frequent Co-Authors

J. Snijder· 2 shared A. Aggarwal· 1 shared A. D. van Zuilen· 1 shared A. J. R. Heck· 1 shared A. Norman· 1 shared B. J. Bosch· 1 shared C. Franck· 1 shared C. J. Jackson· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

J. Snijder

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2 papers

Recent·Most cited

Direct mass spectrometry-based detection and antibody sequencing of Monoclonal Gammopathy of Undetermined Significance from patient serum - a case study.

W. Peng, M. A. den Boer, S. Tamara, N. J. Mokiem, S. P. A. van der Lans, D. Schulte, P.-J. Haas, M. C. Minnema, S. H. M. Rooijakkers, A. D. van Zuilen, A. J. R. Heck, J. Snijder

This paper detects MGUS using LC-MS and determines M-protein sequences from serum, providing molecular detail for monoclonal gammopathies.

bioRxiv · May 22, 2023Immunology

A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein

V. Thijssen, D. L. Hurdiss, O. J. Debski-Antoniak, M. A. Spence, C. Franck, A. Norman, A. Aggarwal, N. J. Mokiem, D. A. A. van Dongen, S. W. Vermeir, M. Liu, W. Li, M. Chatziandreou, T. Donselaar, W. Du, , S. A. K. Jongkees

This paper discovers a macrocyclic peptide that inhibits SARS-CoV-2 and related sarbecoviruses by targeting a conserved site in the spike protein, offering a potential broad-spectrum antiviral.

bioRxiv · Nov 11, 2022 · PreprintBiochemistry