Author

N. J. Waller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metabolomics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

C.-Y. Cheung· 2 shared M. B. McNeil· 2 shared A. L. Peterson· 1 shared B. Nijagal· 1 shared G. Cook· 1 shared G. M. Cook· 1 shared M. T. Chrisp· 1 shared N. E. Seeto· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMicrobiology

C.-Y. Cheung

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Author profile →

2 papers

Recent·Most cited

KatG inactivation generates vulnerabilities in isoniazid resistant strains of Mycobacterium tuberculosis

X. Wang, W. J. Jowsey, C.-Y. Cheung, N. E. Seeto, N. J. Waller, M. T. Chrisp, A. L. Peterson, B. Nijagal, P. C. Fineran, G. M. Cook, S. A. Jackson, M. B. McNeil

The paper identifies vulnerabilities in isoniazid-resistant Mycobacterium tuberculosis strains by analyzing metabolic and transcriptional changes in katG mutants.

bioRxiv · Dec 7, 2023 · PreprintMicrobiology

The evolution of antibiotic resistance is associated with collateral drug phenotypes in Mycobacterium tuberculosis

N. J. Waller, C.-Y. Cheung, G. Cook, M. B. McNeil

This study shows that drug resistance in M. tuberculosis can lead to collateral sensitivity to unrelated drugs, offering new strategies to combat drug-resistant strains.

bioRxiv · Oct 31, 2022 · PreprintMicrobiology