Author

M. B. McNeil

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 5

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 4 Approach:experimental assay· 3 Organism:human· 3 Approach:genetic perturbation / CRISPR· 2 Assay:metabolomics· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

C.-Y. Cheung· 2 shared G. M. Cook· 2 shared N. J. Waller· 2 shared T. Parish· 2 shared A. Korkegian· 1 shared A. L. Peterson· 1 shared B. Berube· 1 shared B. Nijagal· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

C.-Y. Cheung

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

KatG inactivation generates vulnerabilities in isoniazid resistant strains of Mycobacterium tuberculosis

X. Wang, W. J. Jowsey, C.-Y. Cheung, N. E. Seeto, N. J. Waller, M. T. Chrisp, A. L. Peterson, B. Nijagal, P. C. Fineran, G. M. Cook, S. A. Jackson, M. B. McNeil

The paper identifies vulnerabilities in isoniazid-resistant Mycobacterium tuberculosis strains by analyzing metabolic and transcriptional changes in katG mutants.

bioRxiv · Dec 7, 2023 · PreprintMicrobiology

The evolution of antibiotic resistance is associated with collateral drug phenotypes in Mycobacterium tuberculosis

N. J. Waller, C.-Y. Cheung, G. Cook, M. B. McNeil

This study shows that drug resistance in M. tuberculosis can lead to collateral sensitivity to unrelated drugs, offering new strategies to combat drug-resistant strains.

bioRxiv · Oct 31, 2022 · PreprintMicrobiology

Triazolopyrimidines target aerobic respiration in Mycobacterium tuberculosis

C. D. Shelton, M. B. McNeil, L. Flint, D. Russell, B. Berube, A. Korkegian, Y. Ovechkina, T. Parish

This study identifies triazolopyrimidines as inhibitors of Mycobacterium tuberculosis cytochrome bc1 complex, showing resistance linked to QcrB mutations and efficacy against intracellular bacteria.

bioRxiv · Oct 18, 2021Microbiology

Impaired succinate oxidation prevents growth and influences drug susceptibility in Mycobacterium tuberculosis

C. R. Adolph, M. B. McNeil, G. M. Cook

This study shows that impaired succinate oxidation in M. tuberculosis prevents growth and affects drug susceptibility by altering respiratory chain activity and drug responses.

bioRxiv · Jun 21, 2021Microbiology

Cell wall inhibitors increase the accumulation of rifampicin in Mycobacterium tuberculosis

M. B. McNeil, S. Chettiar, D. Awasthi, T. Parish

The paper shows that cell wall inhibitors enhance rifampicin accumulation in Mycobacterium tuberculosis by increasing cellular permeability, suggesting potential for improved tuberculosis treatment combinations.

bioRxiv · Sep 23, 2018Microbiology