Author

N. Kalakonda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

A. Alshayeb· 1 shared A. D'Avola· 1 shared A. F. Khan· 1 shared A. Holroyd· 1 shared A. J. Linley· 1 shared A. J. Steele· 1 shared A. M. Michie· 1 shared A. Mondru· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Alshayeb

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

PKCβ facilitates leukemogenesis in chronic lymphocytic leukaemia by promoting constitutive BCR-mediated signaling

J. Hay, A. Tarafdar, A. Holroyd, H. A. Moka, K. M. Dunn, A. Alshayeb, B. H. Lloyd, J. Cassels, N. Malik, A. F. Khan, I. Sou, J. Lees, H. N. Almuhanna, N. Kalakonda, J. R. Slupsky, A. M. Michie

This study shows PKCβ promotes CLL by enhancing BCR signaling and identifies SP1 as a regulator of PKCβ expression in leukemogenesis.

bioRxiv · Sep 4, 2022 · PreprintCancer Biology

Kinobead Profiling Reveals Reprogramming of B-cell Receptor Signaling in Response to Therapy Within Primary Chronic Lymphocytic Leukemia Cells.

A. J. Linley, L. Karydis, A. Mondru, A. D'Avola, S. Cicconi, R. Griffin, F. Forconi, A. R. Pettitt, N. Kalakonda, A. Rawstron, P. Hillmen, A. J. Steele, D. J. MacEwan, G. Packham, I. Prior, J. Slupsky

This study uses kinobead profiling and mass spectrometry to analyze B-cell receptor signaling changes in CLL cells before and after therapy, revealing adaptive reprogramming in response to treatment.

bioRxiv · Jun 4, 2020Cancer Biology