Author

K. M. Dunn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. M. Michie· 3 shared J. Hay· 3 shared J. Cassels· 2 shared N. Malik· 2 shared A. Alshayeb· 1 shared A. F. J. M. A. Taqi· 1 shared A. F. Khan· 1 shared A. G. West· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCancer Biology

A. M. Michie

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PKCβ facilitates leukemogenesis in chronic lymphocytic leukaemia by promoting constitutive BCR-mediated signaling

J. Hay, A. Tarafdar, A. Holroyd, H. A. Moka, K. M. Dunn, A. Alshayeb, B. H. Lloyd, J. Cassels, N. Malik, A. F. Khan, I. Sou, J. Lees, H. N. Almuhanna, N. Kalakonda, J. R. Slupsky, A. M. Michie

This study shows PKCβ promotes CLL by enhancing BCR signaling and identifies SP1 as a regulator of PKCβ expression in leukemogenesis.

bioRxiv · Sep 4, 2022 · PreprintCancer Biology

Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells

H. Donnelly, E. Ross, Y. Xiao, R. Hermantara, A. F. J. M. A. Taqi, W. S. Doherty-Boyd, J. Cassels, P. M. Tsimbouri, K. M. Dunn, J. Hay, Z. A. Cheng, N. Jain, C. C. West, H. Wheadon, A. M. Michie, , M. J. Dalby

This study develops a bioengineered niche that maintains long-term haematopoietic stem cells by recreating physiological extracellular matrix organisation, supporting their survival and function without media supplementation.

bioRxiv · Jul 28, 2022 · PreprintBioengineering

mTORC1 activity is essential for disease progression in chronic lymphocytic leukemia

N. Malik, J. Hay, K. M. Dunn, R. Nakagawa, O. J. Sansom, A. M. Michie

This study shows that mTORC1 is essential for CLL progression in mice, with rapamycin effectively targeting eEF2 to inhibit proliferation and MCL1 expression.

bioRxiv · Apr 19, 2022 · PreprintCancer Biology