Author

N. Kyritsis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. M. Chapdelaine-Williams· 2 shared F. W. Alt· 2 shared A. Conte· 1 shared A. Y. Ye· 1 shared C.-S. Lee· 1 shared H. Chen· 1 shared H. Hu· 1 shared H. Yoon· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersImmunology

A. M. Chapdelaine-Williams

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2 papers

Recent·Most cited

Physiological role of the 3'IgH CBEs super-anchor in antibody class switching

X. Zhang, H. Yoon, A. M. Chapdelaine-Williams, N. Kyritsis, F. W. Alt

The paper shows that deleting all 3IgH CBEs affects germline transcription and CSR of upstream S regions, except S{gamma}1, and causes aberrant CSR rearrangements.

bioRxiv · Nov 25, 2020Immunology

Loop Extrusion Mediates Physiological Locus Contraction for V(D)J Recombination

H.-Q. Dai, H. Hu, J. Lou, A. Y. Ye, A. M. Chapdelaine-Williams, N. Kyritsis, Y. Zhang, N. Manfredonia, R. Judson, H. Chen, K. Johnson, S. Lin, Z. Ba, A. Conte, R. Casellas, , F. W. Alt

The paper shows that locus contraction and V(D)J recombination are regulated by circumventing CBE scanning impediments through Wapl-dependent cohesin dynamics.

bioRxiv · Jun 30, 2020 · PreprintImmunology