Author

N. Manfredonia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1

Frequent Co-Authors

F. W. Alt· 2 shared R. Judson· 2 shared A. Chapdelaine-Williams· 1 shared A. Conte· 1 shared A. M. Chapdelaine-Williams· 1 shared A. Y. Ye· 1 shared B. F. Haynes· 1 shared C.-S. Lee· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

F. W. Alt

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Loop Extrusion Mediates Physiological Locus Contraction for V(D)J Recombination

H.-Q. Dai, H. Hu, J. Lou, A. Y. Ye, A. M. Chapdelaine-Williams, N. Kyritsis, Y. Zhang, N. Manfredonia, R. Judson, H. Chen, K. Johnson, S. Lin, Z. Ba, A. Conte, R. Casellas, , F. W. Alt

The paper shows that locus contraction and V(D)J recombination are regulated by circumventing CBE scanning impediments through Wapl-dependent cohesin dynamics.

bioRxiv · Jun 30, 2020 · PreprintImmunology

Conditional Antibody Expression to Avoid Central B Cell Deletion in a Humanized HIV-1 Vaccine Mouse Models

M. Tian, K. McGovern, H.-L. Cheng, P. Waddicor, L. Rieble, M. T. Kimble, M. Dao, Y. Chen, E. Cantor, N. Manfredonia, R. Judson, A. Chapdelaine-Williams, D. W. Cain, B. F. Haynes, F. W. Alt

This paper develops a conditional expression strategy to enable mature B cell expression of bnAb precursors in transgenic mice, overcoming developmental blocks caused by bnAb properties.

bioRxiv · Jan 3, 2020Immunology