Author

N. L. Visser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. S. Peeper· 2 shared D. W. Vredevoogd· 2 shared B. de Bruijn· 1 shared C.-P. Lin· 1 shared D. D'Empaire Altimari· 1 shared G. Apriamashvili· 1 shared J. Boshuizen· 1 shared J. D. Londino· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

D. S. Peeper

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2 papers

Recent·Most cited

TSC2 regulates tumor susceptibility to TRAIL-mediated T cell killing by orchestrating mTOR signaling

D. S. Peeper, C.-P. Lin, J. J. H. Traets, D. W. Vredevoogd, N. L. Visser

This study shows TSC2 regulates tumor susceptibility to TRAIL-mediated T cell killing by modulating mTOR signaling and TRAIL receptor expression.

bioRxiv · May 9, 2022Cancer Biology

LOSS OF UBIQUITIN LIGASE STUB1 AMPLIFIES IFNγ-R1/JAK1 SIGNALING AND SENSITIZES TUMORS TO IFNγ

G. Apriamashvili, D. W. Vredevoogd, O. Krijgsman, O. B. Bleijerveld, M. A. Ligtenberg, B. de Bruijn, J. Boshuizen, D. D'Empaire Altimari, N. L. Visser, J. D. Londino, M. Altelaar, D. S. Peeper

This study shows that loss of STUB1 enhances IFNγ signaling and sensitizes tumors to IFNγ, suggesting STUB1 inhibition combined with PD-1 blockade could improve cancer immunotherapy.

bioRxiv · Jul 7, 2020 · PreprintCancer Biology