Author

O. B. Bleijerveld

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Sonnenberg· 1 shared A. Velds· 1 shared A. Zuidema· 1 shared B. de Bruijn· 1 shared D. D'Empaire Altimari· 1 shared D. S. Peeper· 1 shared D. W. Vredevoogd· 1 shared F. J. van der Wal· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCell Biology

A. Sonnenberg

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

PP2A inhibition instructs spliceosome phosphorylation to create splicing vulnerability in colon adenocarcinoma

M. H. Dias, V. Liudkovska, O. B. Bleijerveld, A. Velds, R. Bernards, M. Ciesla

The paper shows that PP2A inhibition in colon cancer alters splicing patterns, leading to genomic instability and potential improvements in immune therapy responses.

bioRxiv · Jul 12, 2023 · PreprintCancer Biology

Proteomic analysis identifies novel binding partners of BAP1

R. Baas, F. J. van der Wal, O. B. Bleijerveld, H. van Attikum, T. K. Sixma

The paper identifies novel BAP1 binding partners in the cytoplasm using AP-MS and validates interactions with HAT1 and COPI subunits.

bioRxiv · Mar 3, 2021Biochemistry

LOSS OF UBIQUITIN LIGASE STUB1 AMPLIFIES IFNγ-R1/JAK1 SIGNALING AND SENSITIZES TUMORS TO IFNγ

G. Apriamashvili, D. W. Vredevoogd, O. Krijgsman, O. B. Bleijerveld, M. A. Ligtenberg, B. de Bruijn, J. Boshuizen, D. D'Empaire Altimari, N. L. Visser, J. D. Londino, M. Altelaar, D. S. Peeper

This study shows that loss of STUB1 enhances IFNγ signaling and sensitizes tumors to IFNγ, suggesting STUB1 inhibition combined with PD-1 blockade could improve cancer immunotherapy.

bioRxiv · Jul 7, 2020 · PreprintCancer Biology

Mechanisms of integrin αVβ5 clustering in flat clathrin lattices

A. Zuidema, W. Wang, M. Kreft, L. te Molder, L. Hoekman, O. B. Bleijerveld, L. Nahidiazar, H. Janssen, A. Sonnenberg

This study identifies molecular mechanisms governing integrin αVβ5 clustering in flat clathrin lattices in human keratinocytes, showing dependence on vitronectin, calcium, and adaptor proteins.

bioRxiv · Sep 26, 2018Cell Biology