DNAJB8 oligomerization is mediated by an aromatic-rich motif that is dispensable for substrate activity
B. D. Ryder, E. Ustyantseva, D. R. Boyer, A. Mendoza-Oliva, M. Kuska, P. M. Wydorski, P. Macierzynska, N. Morgan, M. R. Sawaya, M. I. Diamond, H. H. Kampinga, L. Joachimiak
This paper identifies an aromatic-rich motif in DNAJB8 that mediates oligomerization and shows that disrupting this motif affects oligomerization but not substrate activity.
bioRxiv · Mar 6, 2023Biophysics