RNase L-mediated RNA decay alters 3' end formation and splicing of host mRNAs
J. M. Burke, N. Ripin, M. B. Ferretti, L. A. St Clair, E. R. Worden-Sapper, S. L. Sawyer, R. Perera, K. W. Lynch, R. Parker
This study shows that RNase L-mediated RNA decay causes RNA-binding proteins to shift from cytoplasm to nucleus, altering splicing and 3' end formation of host mRNAs, especially interferons.
bioRxiv · Jan 28, 2022 · PreprintImmunology