Author

C. M. Spalluto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:metagenomics· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

M. V. Humbert· 2 shared A. A. Khromykh· 1 shared A. Amarilla· 1 shared A. Suhrbier· 1 shared B. Sheth· 1 shared C. J. McCormick· 1 shared C. J. Mycroft-West· 1 shared D. J. J. Sng· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

M. V. Humbert

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Mechanisms of SARS-CoV-2 Inactivation using UVC Laser Radiation

G. Devitt, P. B. Johnson, N. Hanrahan, S. I. R. Lane, M. C. Vidale, B. Sheth, J. D. Allen, M. V. Humbert, C. M. Spalluto, R. C. Herve, K. Staples, J. West, R. Forster, N. Divecha, C. J. McCormick, , S. Mahajan

This study investigates the inactivation of SARS-CoV-2 using UVC laser radiation and identifies mechanisms involving RNA damage and disruption of spike protein function.

bioRxiv · Feb 3, 2023Microbiology

Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 By Disrupting The Spike-ACE2 interaction

S. E. Guimond, C. J. Mycroft-West, N. S. Gandhi, J. A. Tree, T. T. Le, C. M. Spalluto, M. V. Humbert, K. R. Buttigieg, N. Coombes, M. J. Elmore, K. Nystrom, J. Said, Y. X. Setoh, A. Amarilla, N. Modhiran, , J. E. Turnbull

This paper shows that pixatimod inhibits SARS-CoV-2 by disrupting the Spike-ACE2 interaction, demonstrating its potential as an anti-COVID-19 therapeutic.

bioRxiv · Jun 24, 2020Microbiology