Cancer BiologybioRxivPreprint
Chemical exhaustion of RPA in cancer treatment
P. S. VanderVere-Carozza, K. S. Pawelczak, N. S. Gavande…·J. J. Turchi
This paper develops RPA inhibitors that induce RPA exhaustion, showing anticancer activity in vitro and in vivo, and identifies RPA expression as a prognostic and predictive biomarker.
DOI 10.1101/2020.11.30.404640