Author

N. S. Muthunayake

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Gega· 2 shared J. M. Schrader· 2 shared J. S. Biteen· 2 shared W. S. Childers· 2 shared A. Ghosh· 1 shared A. Hatami· 1 shared C. B. Mousseau· 1 shared D. T. Tomares· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMicrobiology

A. Gega

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The BR-body proteome contains a complex network of protein-protein and protein-RNA interactions

V. Nandana, I. W. Rathnayaka-Mudiyanselage, N. S. Muthunayake, A. Hatami, C. B. Mousseau, L. A. Ortiz-Rodriguez, J. Vaishnav, M. Collins, A. Gega, K. S. Mallikaarachchi, H. Yassine, A. Ghosh, J. S. Biteen, Y. Zhu, M. M. Champion, , J. M. Schrader

The paper identifies 111 proteins enriched in bacterial RNP bodies (BR-bodies) and shows they form a complex network of protein-protein and protein-RNA interactions that regulate BR-body phase separation and RNA processing.

bioRxiv · Jan 18, 2023 · PreprintMicrobiology

BR-bodies provide selectively permeable condensates that stimulate mRNA decay and prevent release of decay intermediates

N. Al-Husini, D. T. Tomares, Z. Pfaffenberger, N. S. Muthunayake, M. A. Samad, T. Zuo, O. Bitar, J. R. Aretakis, M. H. M. Bharmal, A. Gega, J. S. Biteen, W. S. Childers, J. M. Schrader

The paper identifies RNA substrates of BR-bodies and shows they stimulate mRNA decay while preventing toxic intermediates.

bioRxiv · Jul 5, 2019Biochemistry