Author

N. Al-Husini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. M. Schrader· 3 shared A. Gega· 2 shared A. Vaishnav· 1 shared D. T. Tomares· 1 shared E. Ng· 1 shared I. W. Rathnayaka-Mudiyanselage· 1 shared J. C. Chen· 1 shared J. L. Huang· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiochemistry

J. M. Schrader

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3 papers

Recent·Most cited

Sinorhizobium meliloti BR-bodies promote fitness during host colonization

K. S. Mallikaarachchi, J. L. Huang, S. Madras, R. A. Cuellar, Z. Huang, A. Gega, I. W. Rathnayaka-Mudiyanselage, N. Al-Husini, N. Saldana-Rivera, L. H. Ma, E. Ng, J. C. Chen, J. M. Schrader

This study shows that BR-bodies in Sinorhizobium meliloti enhance mRNA decay efficiency and symbiotic fitness during host colonization.

bioRxiv · Apr 5, 2024Microbiology

Caulobacter crescentus RNase E condensation contributes to autoregulation and fitness

V. Nandana, N. Al-Husini, A. Vaishnav, K. H. Dilrangi, J. M. Schrader

This study shows that RNase E autoregulation in Caulobacter crescentus involves phase-separation and 5 UTR cleavage, enhancing fitness through proper mRNA decay control.

bioRxiv · Dec 15, 2023 · PreprintBiochemistry

BR-bodies provide selectively permeable condensates that stimulate mRNA decay and prevent release of decay intermediates

N. Al-Husini, D. T. Tomares, Z. Pfaffenberger, N. S. Muthunayake, M. A. Samad, T. Zuo, O. Bitar, J. R. Aretakis, M. H. M. Bharmal, A. Gega, J. S. Biteen, W. S. Childers, J. M. Schrader

The paper identifies RNA substrates of BR-bodies and shows they stimulate mRNA decay while preventing toxic intermediates.

bioRxiv · Jul 5, 2019Biochemistry