Author

A. Gega

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:bacteria (other)· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. M. Schrader· 4 shared I. W. Rathnayaka-Mudiyanselage· 2 shared J. R. Aretakis· 2 shared J. S. Biteen· 2 shared K. S. Mallikaarachchi· 2 shared N. Al-Husini· 2 shared N. S. Muthunayake· 2 shared W. S. Childers· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMicrobiology

J. M. Schrader

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Sinorhizobium meliloti BR-bodies promote fitness during host colonization

K. S. Mallikaarachchi, J. L. Huang, S. Madras, R. A. Cuellar, Z. Huang, A. Gega, I. W. Rathnayaka-Mudiyanselage, N. Al-Husini, N. Saldana-Rivera, L. H. Ma, E. Ng, J. C. Chen, J. M. Schrader

This study shows that BR-bodies in Sinorhizobium meliloti enhance mRNA decay efficiency and symbiotic fitness during host colonization.

bioRxiv · Apr 5, 2024Microbiology

The BR-body proteome contains a complex network of protein-protein and protein-RNA interactions

V. Nandana, I. W. Rathnayaka-Mudiyanselage, N. S. Muthunayake, A. Hatami, C. B. Mousseau, L. A. Ortiz-Rodriguez, J. Vaishnav, M. Collins, A. Gega, K. S. Mallikaarachchi, H. Yassine, A. Ghosh, J. S. Biteen, Y. Zhu, M. M. Champion, , J. M. Schrader

The paper identifies 111 proteins enriched in bacterial RNP bodies (BR-bodies) and shows they form a complex network of protein-protein and protein-RNA interactions that regulate BR-body phase separation and RNA processing.

bioRxiv · Jan 18, 2023 · PreprintMicrobiology

BR-bodies provide selectively permeable condensates that stimulate mRNA decay and prevent release of decay intermediates

N. Al-Husini, D. T. Tomares, Z. Pfaffenberger, N. S. Muthunayake, M. A. Samad, T. Zuo, O. Bitar, J. R. Aretakis, M. H. M. Bharmal, A. Gega, J. S. Biteen, W. S. Childers, J. M. Schrader

The paper identifies RNA substrates of BR-bodies and shows they stimulate mRNA decay while preventing toxic intermediates.

bioRxiv · Jul 5, 2019Biochemistry

Absolute measurements of mRNA translation in C. crescentus reveal important fitness costs of vitamin B12 scavenging

J. R. Aretakis, A. Gega, J. M. Schrader

The paper measures mRNA translation in C. crescentus using ribosome profiling, finding that B12-related genes account for ~4.5% of protein synthesis and reveal fitness costs of B12 scavenging.

bioRxiv · Feb 15, 2019Microbiology