Author

W. S. Childers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Biochemistry· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Organism:bacteria (other)· 2 Organism:C. elegans· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

J. M. Schrader· 3 shared A. Gega· 2 shared D. Tomares· 2 shared J. S. Biteen· 2 shared K. A. Kowallis· 2 shared N. S. Muthunayake· 2 shared A. Ghosh· 1 shared A. Hatami· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

J. M. Schrader

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The BR-body proteome contains a complex network of protein-protein and protein-RNA interactions

V. Nandana, I. W. Rathnayaka-Mudiyanselage, N. S. Muthunayake, A. Hatami, C. B. Mousseau, L. A. Ortiz-Rodriguez, J. Vaishnav, M. Collins, A. Gega, K. S. Mallikaarachchi, H. Yassine, A. Ghosh, J. S. Biteen, Y. Zhu, M. M. Champion, , J. M. Schrader

The paper identifies 111 proteins enriched in bacterial RNP bodies (BR-bodies) and shows they form a complex network of protein-protein and protein-RNA interactions that regulate BR-body phase separation and RNA processing.

bioRxiv · Jan 18, 2023 · PreprintMicrobiology

RNase E biomolecular condensates stimulate PNPase activity

M. J. Collins, D. Tomares, J. M. Schrader, W. S. Childers

This study shows RNase E biomolecular condensates enhance PNPase activity, accelerating RNA decay and shaping the transcriptome.

bioRxiv · Jun 6, 2022Biochemistry

Scaffold-scaffold interactions regulate cell polarity in a bacterium

W. Zhao, S. W. Duvall, K. A. Kowallis, C. Zhang, D. Tomares, H. Petitjean, W. S. Childers

The paper identifies a scaffold-scaffold interaction in Caulobacter crescentus that regulates PopZ localization and cell polarity during division.

bioRxiv · Aug 21, 2020 · PreprintMicrobiology

Reversed Signaling Flow of a Bacterial Pseudokinase

K. A. Kowallis, E. M. Silfani, A. P. Kasumu, G. Rong, V. So, W. S. Childers

The paper investigates a reverse signaling mechanism in Caulobacter crescentus, showing that a pseudokinase domain can modulate signaling network activity through conformational changes.

bioRxiv · Oct 24, 2019 · PreprintMicrobiology

BR-bodies provide selectively permeable condensates that stimulate mRNA decay and prevent release of decay intermediates

N. Al-Husini, D. T. Tomares, Z. Pfaffenberger, N. S. Muthunayake, M. A. Samad, T. Zuo, O. Bitar, J. R. Aretakis, M. H. M. Bharmal, A. Gega, J. S. Biteen, W. S. Childers, J. M. Schrader

The paper identifies RNA substrates of BR-bodies and shows they stimulate mRNA decay while preventing toxic intermediates.

bioRxiv · Jul 5, 2019Biochemistry