BR-bodies provide selectively permeable condensates that stimulate mRNA decay and prevent release of decay intermediates
N. Al-Husini, D. T. Tomares, Z. Pfaffenberger, N. S. Muthunayake, M. A. Samad, T. Zuo, O. Bitar, J. R. Aretakis, M. H. M. Bharmal, A. Gega, J. S. Biteen, W. S. Childers, J. M. Schrader
The paper identifies RNA substrates of BR-bodies and shows they stimulate mRNA decay while preventing toxic intermediates.
bioRxiv · Jul 5, 2019Biochemistry