Enhancing natural killer cell function with gp41-targeting bispecific antibodies to combat HIV infection
N. S. Ramadoss, N. Q. Zhao, B. A. Richardson, P. M. Grant, P. S. Kim, C. A. Blish
This study develops bispecific antibodies targeting HIV gp41 and NK cell CD16 to enhance ADCC against HIV-infected cells, showing improved degranulation and killing of infected targets.
bioRxiv · Sep 8, 2019Immunology