Author

N. Sigal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

M. H. Spitzer· 2 shared A. A. Herskovits· 1 shared A. Haber· 1 shared A. Lawless· 1 shared A. M. Cicerchia· 1 shared A. Mehta· 1 shared A. Tal-Mason· 1 shared B. Petrova· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

M. H. Spitzer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy

O.-Y. Revach, A. M. Cicerchia, O. Shorer, B. Petrova, S. Anderson, J. Park, L. Chen, A. Mehta, S. J. Wright, N. McNamee, A. Tal-Mason, G. Cattaneo, P. Tiwari, H. Xie, J. M. Sweere, , K. Yizhak

This study shows that targeting CD38 improves T cell function and restores response to immunotherapy in melanoma models.

bioRxiv · Feb 12, 2024 · PreprintCancer Biology

Listeria monocytogenes TcyKLMN cystine/cysteine transporter facilitates glutathione synthesis and virulence gene expression

A. A. Herskovits, M. Brenner, S. Freidman, A. Haber, I. Borovok, N. Sigal, O. Lewinson

bioRxiv · Sep 7, 2021Microbiology

Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy

F. J. Hartmann, J. Babdor, P. F. Gherardini, E.-A. D. Amir, K. Jones, B. Sahaf, D. M. Marquez, P. Krutzik, E. O'Donnell, N. Sigal, H. T. Maecker, E. Meyer, M. H. Spitzer, S. C. Bendall

The paper presents a mass cytometry workflow for standardized immune monitoring in immunotherapy trials, identifying immune cell signatures and validating its robustness across samples and centers.

bioRxiv · Dec 13, 2018Immunology