Author

D. M. Marquez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 6 Approach:experimental assay· 6 Assay:flow cytometry· 5 Organism:human· 4 Research Focus:cell-cell communication· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2

Frequent Co-Authors

M. H. Spitzer· 6 shared I. Tenvooren· 5 shared K. M. Ansel· 2 shared M. F. Krummel· 2 shared T. L. H. Okholm· 2 shared A. Cheung· 1 shared A. J. Combes· 1 shared A. Mende· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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6 shared papersImmunology

M. H. Spitzer

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6 papers

Recent·Most cited

A mass cytometry approach to track the evolution of T cell responses during infection and immunotherapy by paired T cell receptor repertoire and T cell differentiation state analysis

J. G. Castillo, R. DeBarge, A. Mende, I. Tenvooren, D. M. Marquez, A. Straub, D. H. Busch, M. H. Spitzer, M. DuPage

The paper develops a mass cytometry method to track T cell receptor repertoires and differentiation states during infection and immunotherapy, showing how antigen recognition influences T cell responses.

bioRxiv · Jan 11, 2024 · PreprintImmunology

Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted by metastasis

M. K. Rahim, T. L. H. Okholm, K. B. Jones, E. E. McCarthy, C. C. Liu, J. L. Yee, S. J. Tamaki, D. M. Marquez, I. Tenvooren, K. Wai, A. Cheung, B. R. Davidson, V. Johri, B. Samad, W. E. O'Gorman, , M. H. Spitzer

The paper examines CD8+ T cell responses in human lymph nodes during cancer immunotherapy and finds that metastasis disrupts these responses.

bioRxiv · Nov 8, 2022 · PreprintImmunology

A conserved immune trajectory of recovery in hospitalized COVID-19 patients

T. L. H. Okholm, C. E. Burnett, I. Tenvooren, D. M. Marquez, S. Tamaki, P. M. Sandoval, The UCSF COMET Consortium, C. S. Calfee, C. M. Hendrickson, K. N. Kangelaris, C. R. Langelier, M. F. Krummel, P. G. Woodruff, D. J. Erle, K. M. Ansel, M. H. Spitzer

The paper identifies a conserved immune recovery trajectory in hospitalized COVID-19 patients through longitudinal mass cytometry analysis, linking immune processes to clinical outcomes.

bioRxiv · Mar 15, 2022 · PreprintImmunology

Type 2 innate immunity regulates hair follicle homeostasis to control Demodex pathosymbionts

R. R. Ricardo-Gonzalez, M. E. Kotas, I. Tenvooren, D. M. Marquez, M. S. Fassett, J. Lee, S. G. Daniel, K. Bittinger, R. E. Diaz, J. S. Fraser, K. M. Ansel, M. H. Spitzer, H.-E. Liang, R. M. Locksley

This study shows that type 2 innate immunity, via ILC2s, regulates hair follicle homeostasis and maintains commensal Demodex mite colonization.

bioRxiv · Mar 29, 2021 · PreprintImmunology

Single-cell metabolic dynamics of early activated CD8 T cells during the primary immune response to infection

L. S. Levine, K. J. Hiam, D. M. Marquez, I. Tenvooren, D. C. Contreras, J. C. Rathmell, M. H. Spitzer

The paper examines metabolic dynamics in early activated CD8 T cells during the primary immune response, identifying a transient state with maximal glycolytic and oxidative metabolic activity.

bioRxiv · Jan 21, 2020 · PreprintImmunology

Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy

F. J. Hartmann, J. Babdor, P. F. Gherardini, E.-A. D. Amir, K. Jones, B. Sahaf, D. M. Marquez, P. Krutzik, E. O'Donnell, N. Sigal, H. T. Maecker, E. Meyer, M. H. Spitzer, S. C. Bendall

The paper presents a mass cytometry workflow for standardized immune monitoring in immunotherapy trials, identifying immune cell signatures and validating its robustness across samples and centers.

bioRxiv · Dec 13, 2018Immunology