Author

N. Silverman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:Drosophila· 1 Organism:mouse· 1

Frequent Co-Authors

K. Okuda· 3 shared A. Brown· 2 shared C. L. Grimes· 2 shared R. Bharadwaj· 2 shared S. Mashayekh· 2 shared A. Monahan· 1 shared A. Nagar· 1 shared A. Nandy· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersImmunology

K. Okuda

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3 papers

Recent·Most cited

Synthesis and validation of click-modified of NOD1/2 agonists

R. Bharadwaj, M. V. Anonick, S. Mashayekh, A. Brown, K. A. Wodzanowski, K. Okuda, N. Silverman, C. L. Grimes

This study synthesizes and validates click-modified muropeptides as tools to study NOD1/2 innate immune sensing mechanisms.

bioRxiv · Mar 28, 2023Immunology

Methotrexate inhibition of muropeptide transporter SLC46A2 controls psoriatic skin inflammation

R. Bharadwaj, C. F. Lusi, S. Mashayekh, A. Nagar, R. K. S. Malireddi, G. I. Kane, K. Wodzanowski, A. Brown, K. Okuda, A. Monahan, D. Paik, A. Nandy, M. Anonick, W. E. Goldman, T.-D. Kanneganti, , N. Silverman

The paper shows that SLC46A2 transports DAP-muropeptides to activate NOD1 in keratinocytes, and methotrexate inhibits this transport, reducing psoriatic inflammation.

bioRxiv · Sep 29, 2022 · PreprintImmunology

Leishmania amazonensis sabotages host cell SUMOylation for intracellular survival

K. Okuda, M. C. Franco, A. Yasunaga, R. Gazzinelli, M. Rabinovitch, S. Cherry, N. Silverman

This study identifies SUMOylation inhibition as a mechanism by which Leishmania amazonensis enhances its survival in host macrophages.

bioRxiv · Nov 3, 2021Cell Biology