Author

D. Paik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 3 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

J. R. Huh· 2 shared A. Brown· 1 shared A. Jacobson· 1 shared A. Misra· 1 shared A. Monahan· 1 shared A. Nagar· 1 shared A. Nandy· 1 shared A. S. Devlin· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersImmunology

J. R. Huh

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4 papers

Recent·Most cited

Methotrexate inhibition of muropeptide transporter SLC46A2 controls psoriatic skin inflammation

R. Bharadwaj, C. F. Lusi, S. Mashayekh, A. Nagar, R. K. S. Malireddi, G. I. Kane, K. Wodzanowski, A. Brown, K. Okuda, A. Monahan, D. Paik, A. Nandy, M. Anonick, W. E. Goldman, T.-D. Kanneganti, , N. Silverman

The paper shows that SLC46A2 transports DAP-muropeptides to activate NOD1 in keratinocytes, and methotrexate inhibits this transport, reducing psoriatic inflammation.

bioRxiv · Sep 29, 2022 · PreprintImmunology

Human gut bacteria produce TH17-modulating bile acid metabolites

D. Paik, L. Yao, Y. Zhang, S. Bae, G. D. D'Agostino, E. Kim, E. A. Franzosa, J. Avila-Pacheco, J. E. Bisanz, C. K. Rakowski, H. Vlamakis, R. J. Xavier, P. J. Turnbaugh, R. S. Longman, M. R. Krout, , A. S. Devlin

This study identifies human gut bacteria that produce TH17-modulating bile acid metabolites, showing reduced levels in IBD patients.

bioRxiv · Jan 8, 2021 · PreprintImmunology

Gut-innervating nociceptor neurons protect against enteric infection by modulating the microbiota and Peyer’s patch microfold cells

N. Y. Lai, M. A. Musser, F. A. Pinho-Ribeiro, P. Baral, P. Ma, D. E. Potts, Z. Chen, D. Paik, S. Soualhi, H. Shi, A. Misra, K. Goldstein, K. N. Sivanathan, A. Jacobson, A. Wallrapp, , I. M. Chiu

This study shows gut-innervating nociceptors protect against Salmonella typhimurium infection by modulating microbiota and Peyer’s patch microfold cells.

bioRxiv · Mar 21, 2019 · PreprintImmunology

Bile acid metabolites control Th17 and Treg cell differentiation

S. Hang, D. Paik, S. Devlin, T. Jamma, J. Lu, S. Ha, B. Nelson, S. Kelly, L. Wu, Y. Zheng, F. Rastinejad, M. Krout, M. Fischbach, D. Littman, J. Huh

This study identifies two bile acid metabolites that regulate Th17 and Treg cell differentiation through distinct mechanisms, affecting immune balance in mice.

bioRxiv · Nov 8, 2018Immunology