Author

N. T. Wood

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

P. D. Mabbitt· 2 shared S. Virdee· 2 shared A. Knebel· 1 shared A. Prescott· 1 shared C. L. Scudamore· 1 shared D. Carbajo Lopez· 1 shared D. G. Campbell· 1 shared D. R. Squair· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersBiochemistry

P. D. Mabbitt

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BiochemistrybioRxivPreprintMay 8, 2023

An Atypical E3 Ligase Module in UBR4 Mediates Destabilization of N-degron Substrates

L. Barnsby-Greer, P. D. Mabbitt, M.-A. Dery…·S. Virdee

This study identifies and characterizes a novel E3 ligase module in UBR4, revealing its structural and biochemical specificity for UBE2A and its role in the N-degron pathway.

DOI 10.1101/2023.05.08.539884

humanproteomics

𝕏 PostBluesky

BiochemistrybioRxivPreprintSep 10, 2021

HOIL-1-catalysed ubiquitylation of unbranched glucosaccharides and its activation by ubiquitin oligomers

I. R. Kelsall, E. H. McCrory, Y. Xu…·P. Cohen

This study shows HOIL-1 ubiquitylates unbranched glucosaccharides and its activity is enhanced by ubiquitin oligomers, preventing toxic polysaccharide accumulation.

DOI 10.1101/2021.09.10.459791

mouseproteomics

𝕏 PostBluesky

BiochemistrybioRxivMay 11, 2020

Deubiquitinating Enzyme Amino Acid Profiling Reveals a Class of Ubiquitin Esterases

S. Virdee, V. De Cesare, D. Carbajo Lopez…·N. T. Wood

This study profiles DUBs for threonine esterase and lysine isopeptidase activity, revealing that the MJD class specifically exhibits ubiquitin esterase activity.

DOI 10.1073/pnas.2006947118

humanexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivFeb 8, 2017

FAM83G/PAWS1 controls cytoskeletal dynamics and cell migration through association with the SH3 adaptor CD2AP

G. P. Sapkota, T. D. Cummins, K. Z. L. Wu…·J. C. Smith

The paper shows PAWS1/FAM83G regulates cell migration by controlling F-actin organization and focal adhesion dynamics through its interaction with CD2AP.

DOI 10.1242/jcs.202390

humanimaging

𝕏 PostBluesky