Author

N. V. DiBenedetto

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Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

B. Dupuy· 1 shared J. Peltier· 1 shared L. Bry· 1 shared L. Cersosimo· 1 shared M. Oberkampf· 1 shared V. Yeliseyev· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperMicrobiology

B. Dupuy

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1 paper

Recent·Most cited

The TcdE holin drives toxin secretion and virulence in Clostridioides difficile.

N. V. DiBenedetto, M. Oberkampf, L. Cersosimo, V. Yeliseyev, L. Bry, J. Peltier, B. Dupuy

This study shows that TcdE holin is essential for toxin secretion and virulence in C. difficile, as tcdE mutants exhibit reduced toxin release and less virulence in mice.

bioRxiv · Sep 16, 2023 · PreprintMicrobiology