Author

M. Oberkampf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

B. Dupuy· 3 shared A. Hamiot· 2 shared J. Peltier· 2 shared L. Bry· 2 shared Y. D. Tremblay· 2 shared B. A. Durand· 1 shared I. Martin-Verstraete· 1 shared L. Cersosimo· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersMicrobiology

B. Dupuy

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The TcdE holin drives toxin secretion and virulence in Clostridioides difficile.

N. V. DiBenedetto, M. Oberkampf, L. Cersosimo, V. Yeliseyev, L. Bry, J. Peltier, B. Dupuy

This study shows that TcdE holin is essential for toxin secretion and virulence in C. difficile, as tcdE mutants exhibit reduced toxin release and less virulence in mice.

bioRxiv · Sep 16, 2023 · PreprintMicrobiology

c-di-AMP signaling is required for bile salts resistance and long-term colonization by Clostridioides difficile

M. Oberkampf, A. Hamiot, P. Altamirano-Silva, P. Belles-sancho, Y. D. Tremblay, N. DiBenedetto, R. Seifert, O. SOUTOURINA, L. Bry, B. Dupuy, J. PELTIER

This study identifies c-di-AMP as a key signaling molecule in Clostridioides difficile that regulates osmolyte uptake and bile salt resistance, essential for gut colonization.

bioRxiv · Aug 23, 2021 · PreprintMicrobiology

Metabolic adaption to extracellular pyruvate triggers biofilm formation in Clostridioides difficile

Y. D. Tremblay, B. A. Durand, A. Hamiot, I. Martin-Verstraete, M. Oberkampf, M. Monot, B. Dupuy

This study identifies extracellular pyruvate as a trigger for biofilm formation in C. difficile in the presence of DOC, revealing a mechanism for pathogen persistence in the gut.

bioRxiv · Jan 23, 2021Microbiology