Author

N. Vergnolle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:electrophysiology· 1

Frequent Co-Authors

A. Rubio· 1 shared A.-F. Tilkin-Mariame· 1 shared C. Cherbuy· 1 shared C. Devaud· 1 shared C. Pouzet· 1 shared C. Valle· 1 shared D. C. Bulmer· 1 shared D. Sagnat· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCell Biology

A. Rubio

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

TRPV4 stimulates colonic afferents through mucosal release of ATP and glutamate

M. Y. Meng, L. W. Paine, D. Sagnat, I. Bello, S. Oldroyd, F. Javid, M. T. Harper, J. R. Hockley, E. S. J. Smith, R. M. Owens, L. Alric, E. Buscail, F. Welsh, N. Vergnolle, D. C. Bulmer

This study shows TRPV4 activation in the colon increases afferent activity via mucosal release of ATP and glutamate, suggesting a target for visceral pain treatment.

bioRxiv · Apr 12, 2024Pharmacology & Toxicology

Reconstitution of intestinal stem cell niche in vitro with pharmacological inhibitors or L-WRN conditioned medium differentially regulates epithelial proliferation, differentiation and barrier function in rabbit caecum organoids

E. Mussard, C. Pouzet, V. Helies, G. Pascal, S. Fourre, C. Cherbuy, A. Rubio, N. Vergnolle, S. Combes, M. Beaumont

This paper compares the effects of 2Ki medium and L-WRN conditioned medium on rabbit caecum organoids, showing differential regulation of proliferation, differentiation, and barrier function.

bioRxiv · Apr 2, 2020Cell Biology

Colon-specific immune microenvironment regulates cancer progression versus rejection

G. Trimaglio, A.-F. Tilkin-Mariame, V. Feliu, F. Lauzeral-Vizcaino, M. Tosolini, C. Valle, M. Ayyoub, O. Neyrolles, N. Vergnolle, Y. Rombouts, C. Devaud

This study shows that the colon microenvironment influences whether colorectal tumors progress or are rejected, with distinct immune signatures in each outcome.

bioRxiv · Jan 2, 2020Cancer Biology