Author

N. W. Hempel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Amalric· 1 shared A. R. Cole· 1 shared A. Uboveja· 1 shared C. A. Lyssiotis· 1 shared H. Wang· 1 shared J. Wang· 1 shared K. Cooper· 1 shared K. M. Aird· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Amalric

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1 paper

Recent·Most cited

De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression

N. K. Tangudu, R. Buj, H. Wang, J. Wang, A. R. Cole, A. Uboveja, R. Fang, A. Amalric, P. Sajjakulnukit, M. A. Lyons, K. Cooper, N. W. Hempel, N. W. Snyder, C. A. Lyssiotis, U. R. Chandran, K. M. Aird

This study identifies de novo purine metabolism as a vulnerability in cancers with low p16 expression, showing sensitivity to anti-folate drugs like methotrexate.

bioRxiv · Jul 15, 2023Cancer Biology