Improved conditioning for hematopoietic chimerism induces islet tolerance to cure diabetes
Stephan A. Ramos, Preksha Bhagchandani, Diego M. Burgos, Xueying Gu, Richard Rodríguez, Nadia Nourin, Martin Neukam, Shiva Pathak, Judith A. Shizuru, Seung K. Kim
This study identifies a conditioning regimen that promotes mixed hematopoietic chimerism and islet tolerance to cure diabetes in mice with minimal radiation.
JCI Insight · Apr 9, 2026Peer-reviewedImmunology