Author

Naemeh Pourshafie

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 2

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Greg DonahueiD· 2 shared Shelley L. BergeriD· 2 shared Charly Ryan GoodiD· 1 shared Connor HoganiD· 1 shared Daniel C. XuiD· 1 shared Desi C. AlexanderiD· 1 shared Hanna Sas‐NowosielskaiD· 1 shared Hong Wei XuiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersNeuroscience

Greg DonahueORCID

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2 papers

Recent·Most cited

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedJan 9, 2026

ACSS2 upregulation enhances neuronal resilience to aging and tau-associated neurodegeneration

Naemeh Pourshafie, Desi C. Alexander, Hong Wei Xu…·Shelley L. Berger

This study shows that increasing ACSS2 levels protects neurons from age-related and tau-induced decline by enhancing synaptic and longevity gene expression.

4 citationstop 1%

mousebulk RNA-seq

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NeurosciencebioRxivPreprintSep 18, 2023

Histone acetylation in an Alzheimer's disease cell model promotes homeostatic amyloid-reducing pathways

Daniel C. Xu, Hanna Sas‐Nowosielska, Greg Donahue…·Shelley L. Berger

The paper investigates how reducing histone acetylation in Alzheimer's disease models affects amyloid-reducing pathways and amyloid-beta secretion.

DOI 10.1101/2023.09.18.558276

humanbulk RNA-seq

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