Hanna Sas‐Nowosielska

The paper identifies SWING regions as chromatin domains that mediate gene regulation through interactions with nuclear speckles and the lamina, showing their role in development and disease.

This study shows neuronal activation remodels nuclear speckles' organization and protein composition in rat hippocampal neurons without causing stress or cell death, and these changes depend on transcription and splicing.

The paper investigates how reducing histone acetylation in Alzheimer's disease models affects amyloid-reducing pathways and amyloid-beta secretion.