Charly Ryan Good

Expanding the HIF-2α proteomic interactome with TurboID proximity labeling.

This study expands the HIF-2α proteomic interactome using TurboID proximity labeling, identifying 329 novel interactors and linking some to poor patient survival in breast cancer.

Deciphering the role of histone modifications in memory and exhausted CD8 T cells

This study identifies how histone modifications regulate gene expression in memory and exhausted CD8 T cells, revealing distinct epigenetic programs between these cell types.

Histone acetylation in an Alzheimer's disease cell model promotes homeostatic amyloid-reducing pathways

The paper investigates how reducing histone acetylation in Alzheimer's disease models affects amyloid-reducing pathways and amyloid-beta secretion.

Comparison of genotoxic vs. non-genotoxic stabilization of p53 provides insight into parallel stress-responsive transcriptional networks

The paper compares genotoxic and non-genotoxic p53 activation in human fibroblasts, showing similar genome-wide binding and chromatin changes but distinct inflammatory gene expression patterns.