Hsp70 chaperones, Ssa1 and Ssa2, limit poly(A) binding protein aggregation
Hannah E. Buchholz, Sean A. Martin, Jane E. Dorweiler, Claire M. Radtke, Adam Knier, Natalia B. Beans, Anita L. Manogaran
This study shows that Hsp70 chaperones Ssa1 and Ssa2 prevent aggregation of the poly(A) binding protein Pab1 in yeast, and their loss leads to age-related protein aggregation.
Molecular Biology of the Cell · Apr 9, 2025Peer-reviewedCell Biology