Author

Hannah E. Buchholz

Marquette UniversityORCID 0000-0003-3040-1596Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Organism:yeast· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Anita L. ManogaraniD· 2 shared Jane E. Dorweiler· 2 shared Adam KnieriD· 1 shared Claire M. Radtke· 1 shared Derek C. ProsseriD· 1 shared Emily Mitchell SontagiD· 1 shared Natalia B. Beans· 1 shared Sean A. MartiniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

Anita L. ManogaranORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintNov 8, 2025

Stress granules and protein aggregates reveal intracellular resource competition

Hannah E. Buchholz, Sean A. Martin, Jane E. Dorweiler…·Anita L. Manogaran

This study shows that competition for molecular chaperones limits stress granule disassembly, leading to their persistence and solidification, potentially contributing to neurodegenerative diseases.

2 citations

yeastproteomics

𝕏 PostBluesky

Cell BiologyMolecular Biology of the CellPeer-reviewedApr 9, 2025

Hsp70 chaperones, Ssa1 and Ssa2, limit poly(A) binding protein aggregation

Hannah E. Buchholz, Sean A. Martin, Jane E. Dorweiler…·Anita L. Manogaran

This study shows that Hsp70 chaperones Ssa1 and Ssa2 prevent aggregation of the poly(A) binding protein Pab1 in yeast, and their loss leads to age-related protein aggregation.

4 citations

yeastproteomics

𝕏 PostBluesky