Anita L. Manogaran

This study shows that Hsp70 chaperones limit intracellular TTR aggregation in yeast, suggesting their decline may contribute to age-related TTR amyloidosis.

This study shows that competition for molecular chaperones limits stress granule disassembly, leading to their persistence and solidification, potentially contributing to neurodegenerative diseases.

This study shows that Hsp70 chaperones Ssa1 and Ssa2 prevent aggregation of the poly(A) binding protein Pab1 in yeast, and their loss leads to age-related protein aggregation.

This study shows that actin networks influence both the formation and propagation of [PSI+] and [PIN+] prions in yeast by affecting prion particle inheritance and stability.