Autophagy inhibition rescues structural and functional defects caused by the loss of mitochondrial chaperone Hsc70-5/mortalin in Drosophila
Jun‐yi Zhu, Shabab B. Hannan, Nina M. Dräger, Natalia Vereshchagina, Ann-Christin Krahl, Yulong Fu, Christopher J. H. Elliott, Zhe Han, Thomas Robert Jahn, Tobias M. Rasse
The paper investigates the role of Hsc70-5/mortalin loss in Drosophila Parkinson disease models and shows that autophagy inhibition rescues multiple phenotypes.
Autophagy · Jan 6, 2021Peer-reviewedGenetics