Author

Jun‐yi Zhu

Children's NationalORCID 0000-0002-4517-101XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Zhe HaniD· 3 shared Yulong FuiD· 2 shared Ann-Christin Krahl· 1 shared Antentor Othrell Hinton Jr.iD· 1 shared Avi Z. RosenbergiD· 1 shared Christopher J. H. ElliottiD· 1 shared Daniela ČihákováiD· 1 shared Dao‐Fu DaiiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersPathology

Zhe HanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Senescence and DNA Damage-Induced Inflammation Drive Heart Failure with Preserved Ejection Fraction in Cardiovascular Kidney Metabolic Syndrome

Dao‐Fu Dai, Jun‐yi Zhu, Meng Qiu Gao, Kaihao Wang, Nastaran Daneshgar, Xiaoping Yang, Virginia Shalkey Hahn, Monica Vladut Talor, Daniela Čiháková, Avi Z. Rosenberg, Antentor Othrell Hinton Jr., Zhe Han

This study identifies DNA damage-driven senescence and ZBP1-cGAS-STING signaling as conserved mechanisms linking cardiovascular-kidney-metabolic comorbidities to HFpEF.

bioRxiv · Apr 16, 2026 · PreprintPathology

HIV-1 Nef acts in synergy with APOL1-G1 to induce nephrocyte cell death in a new Drosophila model of HIV-related kidney diseases

Jun‐yi Zhu, Yulong Fu, Joyce van de Leemput, Jing Yu, Jinliang Li, Patricio E. Ray, Zhe Han

This paper introduces a Drosophila model to study HIV-1 Nef and APOL1-G1 interaction, showing they synergistically induce ER stress and nephrocyte cell death.

Disease Models & Mechanisms · Jul 1, 2025Peer-reviewedMolecular Biology

Autophagy inhibition rescues structural and functional defects caused by the loss of mitochondrial chaperone Hsc70-5/mortalin in Drosophila

Jun‐yi Zhu, Shabab B. Hannan, Nina M. Dräger, Natalia Vereshchagina, Ann-Christin Krahl, Yulong Fu, Christopher J. H. Elliott, Zhe Han, Thomas Robert Jahn, Tobias M. Rasse

The paper investigates the role of Hsc70-5/mortalin loss in Drosophila Parkinson disease models and shows that autophagy inhibition rescues multiple phenotypes.

Autophagy · Jan 6, 2021Peer-reviewedGenetics