Infrapatellar Fat Pad Extracellular Vesicles Induce a Pro-Angiogenic VEGFAhigh/BMP4low Switch in Articular Chondrocytes: Implications for Chondrosarcoma
Joshua M. J. Price, Caitlin Ditchfield, Hussein Farah, Bethy Airstone, Natalie Lachlan-Jiraskova, Edward T. Davis, Simon Wyn Jones
This study shows that infrapatellar fat pad extracellular vesicles increase VEGFA and decrease BMP4 in chondrocytes, promoting angiogenesis relevant to chondrosarcoma.
bioRxiv · Aug 25, 2026 · PreprintCancer Biology