Author

Natalie R. Sontag

Tufts University

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Microbiology· 1

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Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

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Alwyn M. V. EckeriD· 1 shared Ana Ruiz ManzanoiD· 1 shared Eric A. GalburtiD· 1 shared Shumin TaniD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperMicrobiology

Alwyn M. V. EckerORCID

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1 paper

Recent·Most cited

MicrobiologyPLoS GeneticsPeer-reviewedFeb 12, 2026

Serine/threonine protein kinase phosphorylation of DosR alters target gene transcription mechanics and regulates Mycobacterium tuberculosis sensitivity to nitric oxide stress

Natalie R. Sontag, Ana Ruiz Manzano, Alwyn M. V. Ecker…·Shumin Tan

This study shows that STPK phosphorylation of DosR in Mtb reduces its transcriptional activity and alters its response to nitric oxide stress, highlighting a regulatory interaction between STPKs and TCSs.

1 citation

bacteria (other)DNA methylation

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