Subtractive Interaction Proteomics Reveal a Network of Signaling Pathways Activated by an Oncogenic Transcription Factor in Acute Myeloid Leukemia
Nathalie Guillen, Maria Wieske, Andreas Otto, Afsar Ali Mian, Michal Rokicki, Carol Guy, Caroline Alvares, Paul Hole, Hannelore Held, Oliver Gerhard Ottmann, Dörte Becher, Marieangela Wilson, Kate J. Heesom, Martin Ruthardt, Claudia Chiriches
This study uses subtractive interaction proteomics to identify signaling pathways activated by the t(6;9)-DEK/CAN oncogene in AML, revealing potential therapeutic targets.
bioRxiv · Nov 7, 2018 · PreprintCancer Biology