Author

Nathan J. Spann

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Christopher K. GlassiD· 2 shared Marten A. HoeksemaiD· 2 shared Zeyang SheniD· 2 shared An ZhengiD· 1 shared Casey E. RomanoskiiD· 1 shared Gregory J. FonsecaiD· 1 shared Inge R. HoltmaniD· 1 shared Isidoro CoboiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenomics

Christopher K. GlassORCID

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2 papers

Recent·Most cited

Systematic analysis of naturally occurring insertions and deletions that alter transcription factor spacing identifies tolerant and sensitive transcription factor pairs

Zeyang Shen, Rick Z. Li, Thomas A Prohaska, Marten A. Hoeksema, Nathan J. Spann, Jenhan Tao, Gregory J. Fonseca, Thomas Le, Lindsey K. Stolze, Mashito Sakai, Casey E. Romanoski, Christopher K. Glass

The paper systematically analyzes naturally occurring insertions and deletions (InDels) to assess their impact on transcription factor spacing and identifies tolerant and sensitive TF pairs.

eLife · Jan 20, 2022Peer-reviewedGenomics

Mechanisms underlying divergent responses of genetically distinct macrophages to IL-4

Marten A. Hoeksema, Zeyang Shen, Inge R. Holtman, An Zheng, Nathan J. Spann, Isidoro Cobo, Melissa Gymrek, Christopher K. Glass

The paper identifies how non-coding genetic variation affects macrophage responses to IL-4 by analyzing SNP and InDel effects across five inbred mouse strains.

Science Advances · Jun 16, 2021Peer-reviewedGenomics