Author

Natsuki Ide

University of Tsukuba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Akira ShibuyaiD· 2 shared Chigusa Nakahashi-OdaiD· 2 shared Kazuko ShibuyaiD· 2 shared Akiko Iguchi‐ManakaiD· 1 shared Eri SugiyamaiD· 1 shared Fumie AbeiD· 1 shared Genki OkumuraiD· 1 shared Hideaki TaharaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Akira ShibuyaORCID

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2 papers

Recent·Most cited

Soluble CD155 immune complexes reprogram DNAM-1 signaling to potentiate antitumor immunity

Shota Kinoshita, Tomohei Matsuo, Naoto Takeuchi, Genki Okumura, Natsuki Ide, Akiko Iguchi‐Manaka, Soontae Gwon, Eri Sugiyama, Shohei Koyama, Hideaki Tahara, Chigusa Nakahashi-Oda, Akira Shibuya, Kazuko Shibuya

This paper identifies soluble CD155 as a systemic checkpoint that suppresses DNAM-1 signaling, leading to resistance to immune checkpoint inhibitors, and shows that an anti-sCD155 antibody can reprogram this signaling to enhance antitumor immunity.

bioRxiv · May 19, 2026 · PreprintImmunology

DNAM-1 immunoreceptor integrates innate and adaptive immune programs to drive intestinal inflammation

Natsuki Ide, kazuki Sato, Kyoko Oh‐oka, Mariana Sylvia Almeida, Fumie Abe, Tae-hyeong Kim, Chigusa Nakahashi-Oda, Kazuko Shibuya, Akira Shibuya

This study identifies DNAM-1 as a key integrator of innate and adaptive immune responses in intestinal inflammation, showing it drives colitis through distinct mechanisms in ILC3s and dendritic cells and highlights its potential as a therapeutic target.

bioRxiv · Apr 1, 2026 · PreprintImmunology