K2P Channels Regulate Presynaptic Organisation through a Membrane Potential-Independent Mechanism
Jun Meng, Neeraja Ramakrishnan, Yi Li, Thomas Boulin, Shangbang Gao, Mei Zhen, Isabel Beets, William R Schafer
This study identifies a membrane potential-independent role for the K2P channel TWK-40 in regulating presynaptic organisation through intracellular potassium levels and interactions with PYK-1 and transcription factors.
bioRxiv · Aug 25, 2026 · PreprintMolecular Biology