Optogenetic recruitment of hypothalamic corticotrophin-releasing-hormone (CRH) neurons reduces motivational drive
Caitlin S. Mitchell, Erin J. Campbell, Simon D. Fisher, Laura M. Stanton, Nicholas J. Burton, Amy J. Pearl, Gavan P. McNally, Jaideep Singh Bains, Tamás Füzesi, Brett Anthony Graham, Elizabeth E. Manning, Christopher V. Dayas
This study shows that optogenetic activation of hypothalamic CRH neurons increases stress-related behaviors and reduces sucrose motivation, suggesting a role for these neurons in motivational drive.
Translational Psychiatry · Jan 8, 2024Peer-reviewedNeuroscience